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Model picks & player props
Seattle Seahawks
VS
San Francisco 49ers

Seattle Seahawks vs San Francisco 49ers Picks & Predictions

Model updated Sep 10, 3:57AM UTC

We checked every price on this game against our own numbers. The green ones are the bets worth more than they should be.

NFL
San Francisco
Sun 4 Jan 2026, 1:00AM
20
Game markets graded
0
Props graded
The model's one call for this gamethe prediction, first
Over 48.5 Total Points -105

The model graded 20 markets for Seattle Seahawks vs San Francisco 49ers (NFL) and this is the one it backs hardest — HIGH confidence. A $100 bet returns about $195 if it lands. This one is free — every other market and all player props are Pro. Tip-off Sun 4 Jan 2026, 1:00AM at San Francisco.

Our confidenceHigh
Chance to win61.0%
The price says51.3%
Best price-105
The rest of this game's boardgraded market by market
Total Points Over 48.5 High61% chance -105
Total Points High61% chance
Spread Lean59% chance
Spread Lean59% chance
Moneyline Lean54% chance
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%

Seattle Seahawks and San Francisco 49ers last met on Sun 4 Jan 2026. What follows is the model's graded record from that game; a new preview appears here the moment the next one is priced. Today's board: every NFL game priced right now.

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This game is done — from the model’s graded calls on this game
Kyle Juszczyk Under 1.5 · $100 returned $142

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Our call on this game: 1 pick on the board · logged before tip-offSee the picks

Game picks

GOOD PRICE in green
Total Points
Over
47.5
+ 19 more markets
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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
OverTotal PointsThe model likes this price 🔒 Unlock with Pro
OverTotal PointsThe model likes this price 🔒 Unlock with Pro
San Francisco 49ersSpreadThe model likes this price 🔒 Unlock with Pro
San Francisco 49ersSpreadThe model likes this price 🔒 Unlock with Pro
San Francisco 49ersMoneylineThe model likes this price 🔒 Unlock with Pro

Which price is actually worth taking?

Pro shows you, in plain English, how far each price is off — and how much to put on it. No maths needed on your side.

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Injuries & who's out

Injuries & availability

Seattle Seahawks

  • Sam Darnold QBOut
  • Nick Emmanwori SOut
  • Jalen Milroe QBOut
  • Tory Horton WROut
  • Beau Stephens GOut
  • Mike Morris DEOut
  • Ty Okada SOut
  • Nick Kallerup TEOut
  • Zach Charbonnet RBOut
  • Irv Charles WROut
  • Terrion Arnold CBOut

San Francisco 49ers

  • George Kittle TEQuestionable
  • Alfred Collins DTOut
  • Dre Greenlaw LBQuestionable
  • Renardo Green CBQuestionable
  • Romello Height DEQuestionable
  • Kyle Juszczyk FBQuestionable
  • Nick Bosa DEQuestionable
  • James Thompson Jr. DTQuestionable
  • Mykel Williams DEOut
  • Gracen Halton DTQuestionable
  • Nate Hobbs CBOut
  • Sam Okuayinonu DTOut
  • Nick Martin LBOut
Availability updated Sep 10, 1:38AM UTC — NFL availability is season-pending (off-season); treat as a placeholder until the season opens. · refreshed roughly every 4 hours.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For Seattle Seahawks vs San Francisco 49ers: Outdoors with 4 mph wind, 59°F — stronger wind and cold both nudge totals and the kicking game down, and 24 players are listed out or questionable across both sides.
FactorThis fixture
Roof / venueopen-air outdoor
Surfacenatural grass
Wind4 mph
Temperature59°F
Availability24 listed out or questionable (see Who's out above)

General rule: sustained wind above ~15 mph and hard cold both drag NFL totals and kicking numbers down, while a key skill-position player being out shifts target and touch share to his backups.

Pro — weather & injury-adjusted view

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Betting angles

Markets & form
MoneylineSan Francisco 49ers to winNo line posted

San Francisco 49ers vs Seattle Seahawks moneyline — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Point SpreadSan Francisco 49ers spreadNo line posted

San Francisco 49ers vs Seattle Seahawks spread — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Total PointsSeahawks @ 49ersNo line posted

San Francisco 49ers vs Seattle Seahawks game total — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Seattle Seahawks @ San Francisco 49ers — what the model found

Our model graded 20 betting markets for Seattle Seahawks at San Francisco 49ers — 20 on the game itself and 0 on individual players. One pick is free on this page.

20
Game markets graded

The model checked every betting market for this game and graded 20 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 19 graded calls for this game — with how much to bet on each — are for members.
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Seattle Seahawks vs San Francisco 49ers — recent results

San Francisco 49ers have won 3 of their last 5 games; Seattle Seahawks have won 2 of their last 5.

San Francisco 49ers — last 5
ResultScoreOpponentWhere
W18–12LVAway
W41–17LACAway
L13–19TENHome
L6–41SEAAway
W23–19PHIAway
Seattle Seahawks — last 5
ResultScoreOpponentWhere
D9–9KCAway
L16–19TENAway
L7–17DALHome
W29–13NEAway
W31–27LARHome

Seattle Seahawks vs San Francisco 49ers — recent meetings

These two have met 2 times recently: San Francisco 49ers won 0, Seattle Seahawks won 2.

DateSan Francisco 49ersSeattle SeahawksWinner
Jan 18641Seattle Seahawks
Jan 4313Seattle Seahawks

Who’s out or in doubt

24 players are listed as out or in doubt for this game.

San Francisco 49ers
PlayerStatus
George Kittle TEQUESTIONABLE
Alfred Collins DTOUT
Dre Greenlaw LBQUESTIONABLE
Renardo Green CBQUESTIONABLE
Romello Height DEQUESTIONABLE
Kyle Juszczyk FBQUESTIONABLE
Nick Bosa DEQUESTIONABLE
James Thompson Jr. DTQUESTIONABLE
Seattle Seahawks
PlayerStatus
Sam Darnold QBOUT
Nick Emmanwori SOUT
Jalen Milroe QBOUT
Tory Horton WROUT
Beau Stephens GOUT
Mike Morris DEOUT
Ty Okada SOUT
Nick Kallerup TEOUT

The full availability report — with what each missing player means for the bets — is further down this page.

About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for Seattle Seahawks vs San Francisco 49ers in the NFL. You may also see this matchup written as Seahawks vs 49ers, or as 49ers vs Seahawks. The most recent game between them was Sunday 4 January 2026 at San Francisco. The model has generated 20 game picks for this matchup. Review the picks and historical data above to guide your NFL betting strategy for this matchup.

Head-to-head record

Final scores · 26 meetings on record
Seattle Seahawks 17–9 across the last 26 meetings · these games average 43.1 points (meetings on record since 2015)
DateGameScoreWinner
18 Jan 2026San Francisco 49ers @ Seattle Seahawks41–6Seattle Seahawks
17 Jan 2026San Francisco 49ers @ Seattle Seahawks41–6Seattle Seahawks
4 Jan 2026Seattle Seahawks @ San Francisco 49ers3–13Seattle Seahawks
3 Jan 2026Seattle Seahawks @ San Francisco 49ers3–13Seattle Seahawks
7 Sep 2025San Francisco 49ers @ Seattle Seahawks13–17San Francisco 49ers
17 Nov 2024Seattle Seahawks @ San Francisco 49ers17–20Seattle Seahawks
10 Oct 2024San Francisco 49ers @ Seattle Seahawks24–36San Francisco 49ers
10 Dec 2023Seattle Seahawks @ San Francisco 49ers28–16San Francisco 49ers
23 Nov 2023San Francisco 49ers @ Seattle Seahawks13–31San Francisco 49ers
14 Jan 2023Seattle Seahawks @ San Francisco 49ers41–23San Francisco 49ers

Table shows the last 10 — the record above counts all 26 meetings on file.

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