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Model picks & player props
Tampa Bay Buccaneers
VS
Buffalo Bills

Tampa Bay Buccaneers vs Buffalo Bills Picks & Predictions

Model updated Sep 10, 4:44AM UTC

We checked every price on this game against our own numbers. The green ones are the bets worth more than they should be.

NFL
Buffalo
Sun 16 Nov 2025, 6:00PM
6
Game markets graded
0
Props graded
The model's one call for this gamethe prediction, first
Tampa Bay Buccaneers 5.5 Spread -102

The model graded 6 markets for Tampa Bay Buccaneers vs Buffalo Bills (NFL) and this is the one it backs hardest — a lean, not a lock. A $100 bet returns about $198 if it lands. This one is free — every other market and all player props are Pro. Tip-off Sun 16 Nov 2025, 6:00PM at Buffalo.

Our confidenceLean
Chance to win58.7%
The price says50.5%
Best price-102
The rest of this game's boardgraded market by market
Spread Tampa Bay Buccaneers 5.5 Lean59% chance -102
Spread Lean59% chance —
Spread Lean59% chance —
High = 60%+ chance to win · Lean = 40–60% · Long-shot = under 40%
Every NFL game on today's board →

Tampa Bay Buccaneers and Buffalo Bills last met on Sun 16 Nov 2025. What follows is the model's graded record from that game; a new preview appears here the moment the next one is priced. Today's board: every NFL game priced right now.

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This game is done — from the model’s graded calls on this game
James Cook Over 24.5 · $100 returned $390

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Every pick is logged and graded — nothing hidden after the fact. See the verified record
Our call on this game: 2 picks on the board · logged before tip-offSee the picks

Game picks

GOOD PRICE in green
Spread
Tampa Bay Buccaneers
+6.5
-120
+ 5 more markets
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All 6 game markets and 0 player props for this matchup — every line, every call the model backs — plus every pick across the slate. Join 56,727+ members.

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Calibrated model vs market

Our chance vs the price, market by market
PickMarketModel lean
Tampa Bay BuccaneersSpreadThe model likes this price 🔒 Unlock with Pro
Tampa Bay BuccaneersSpreadThe model likes this price 🔒 Unlock with Pro
Tampa Bay BuccaneersSpreadThe model likes this price 🔒 Unlock with Pro

Which price is actually worth taking?

Pro shows you, in plain English, how far each price is off — and how much to put on it. No maths needed on your side.

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Injuries & who's out

Injuries & availability

Tampa Bay Buccaneers

  • Rueben Bain Jr. LBQuestionable
  • Christian Rozeboom LBQuestionable
  • Justin Skule OTQuestionable
  • Sean Tucker RBQuestionable
  • Jalen McMillan WRQuestionable
  • Josh Hayes CBOut
  • Mohamed Kamara LBOut
  • David Sills V WROut
  • Deshawn McKnight DTOut

Buffalo Bills

  • T.J. Sanders DTQuestionable
  • Jordan Hancock CBQuestionable
  • Ty Johnson RBQuestionable
  • Jedrick Wills Jr. OTQuestionable
  • Tyrell Shavers WROut
  • Dorian Strong CBOut
  • Zane Durant DTOut
  • Jude Bowry OTQuestionable
Availability updated Sep 10, 1:29AM UTC — NFL availability is season-pending (off-season); treat as a placeholder until the season opens. · refreshed roughly every 4 hours.

Weather & injury impact for this fixture

Conditions · who's out · how it moves the number
For Tampa Bay Buccaneers vs Buffalo Bills: Weather isn't a tracked factor for this fixture, and 17 players are listed out or questionable across both sides.
FactorThis fixture
Availability17 listed out or questionable (see Who's out above)

General rule: sustained wind above ~15 mph and hard cold both drag NFL totals and kicking numbers down, while a key skill-position player being out shifts target and touch share to his backups.

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Betting angles

Markets & form
MoneylineBuffalo Bills to winNo line posted

Buffalo Bills vs Tampa Bay Buccaneers moneyline — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Point SpreadTampa Bay Buccaneers spreadNo line posted

Tampa Bay Buccaneers vs Buffalo Bills spread — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Total PointsBuccaneers @ BillsNo line posted

Buffalo Bills vs Tampa Bay Buccaneers game total — the live line, our model's read and how the free board has gone so far, tracked every game week on BetBetter.

Tampa Bay Buccaneers @ Buffalo Bills — what the model found

Our model graded 6 betting markets for Tampa Bay Buccaneers at Buffalo Bills — 6 on the game itself and 0 on individual players. One pick is free on this page.

6
Game markets graded

The model checked every betting market for this game and graded 6 of them. One pick is free on this page — the one the model likes most. Scroll down to see it.

🔒 The other 5 graded calls for this game — with how much to bet on each — are for members.
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Tampa Bay Buccaneers vs Buffalo Bills — recent results

Buffalo Bills have won 4 of their last 5 games; Tampa Bay Buccaneers have won 3 of their last 4.

Buffalo Bills — last 5
ResultScoreOpponentWhere
W28–27PITHome
W31–7CLEAway
W29–14CARHome
L30–33DENAway
W27–24JAXAway
Tampa Bay Buccaneers — last 4
ResultScoreOpponentWhere
L0–19JAXAway
W16–15KCHome
W24–16NYJAway
W16–14CARHome

Who’s out or in doubt

17 players are listed as out or in doubt for this game.

Buffalo Bills
PlayerStatus
T.J. Sanders DTQUESTIONABLE
Jordan Hancock CBQUESTIONABLE
Ty Johnson RBQUESTIONABLE
Jedrick Wills Jr. OTQUESTIONABLE
Tyrell Shavers WROUT
Dorian Strong CBOUT
Zane Durant DTOUT
Jude Bowry OTQUESTIONABLE
Tampa Bay Buccaneers
PlayerStatus
Rueben Bain Jr. LBQUESTIONABLE
Christian Rozeboom LBQUESTIONABLE
Justin Skule OTQUESTIONABLE
Sean Tucker RBQUESTIONABLE
Jalen McMillan WRQUESTIONABLE
Josh Hayes CBOUT
Mohamed Kamara LBOUT
David Sills V WROUT

The full availability report — with what each missing player means for the bets — is further down this page.

About this matchup

How we read the game

This page tracks the Bet Better model's pick history and predictions for Tampa Bay Buccaneers vs Buffalo Bills in the NFL. You may also see this matchup written as Buccaneers vs Bills, or as Bills vs Buccaneers. The most recent game between them was Sunday 16 November 2025 at Buffalo. The model has generated 6 game picks for this matchup. Review the picks and historical data above to guide your NFL betting strategy for this matchup.

Head-to-head record

Final scores · 4 meetings on record
Buffalo Bills 3–1 across the last 4 meetings · these games average 58.8 points (meetings on record since 2017)
DateGameScoreWinner
16 Nov 2025Tampa Bay Buccaneers @ Buffalo Bills44–32Buffalo Bills
26 Oct 2023Tampa Bay Buccaneers @ Buffalo Bills24–18Buffalo Bills
12 Dec 2021Buffalo Bills @ Tampa Bay Buccaneers33–27Tampa Bay Buccaneers
22 Oct 2017Tampa Bay Buccaneers @ Buffalo Bills30–27Buffalo Bills

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Today's selected board

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