On Friday 11 September 2026, Louisville Cardinals play Villanova Wildcats in college football. Our model likes 2 bets here. The one it likes most is Louisville Cardinals -37.5 on the Line, priced at -110 when we wrote this. Here is the thinking behind each pick, in plain English.
Louisville Cardinals -37.5 on the Line (-110)
Odds available at Fanatics at time of publishing
On Friday 11 September 2026, Louisville Cardinals host Villanova Wildcats in college football. The bet we are looking at is Louisville Cardinals -37.5 Point Spread. On this line Louisville Cardinals give up 37.5 points before the game starts, so they have to win by more than 37.5. This is one of the bookmaker's alternate lines, not the main one, so the price is different. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. That price was showing at Fanatics. Our model likes this one a lot. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move. It was priced at -110 when we wrote this, so a $10 bet returns $19.09 if it lands. The number next to the team is the handicap, and that team's score is adjusted by it before the bet is settled. This is an alternate line, so it is not the main number on the board and the price moves with it. The bookmakers have this as a slight favourite. Our model leans this way without loving it. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.
Under 55 Total Points (+110)
Odds available at Fanatics at time of publishing
On Friday 11 September 2026, Louisville Cardinals host Villanova Wildcats in college football. The bet we are looking at is Under 55 Total Points. This wins if the two sides score fewer than 55 points between them. This is one of the bookmaker's alternate lines, not the main one, so the price is different. It was priced at +110 when we wrote this, so a $10 bet returns $21 if it lands. That price was showing at Fanatics. Our model has this one as a long shot, so keep the bet small. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move. It was priced at +110 when we wrote this, so a $10 bet returns $21 if it lands. This is an alternate line, so it is not the main number on the board and the price moves with it. This one is priced as an outside chance. Our model has this as a long shot, so keep the stake small. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.
That is how our model reads Louisville Cardinals v Villanova Wildcats. Prices move, so check the price at your bookmaker before you back anything. And if a game does not feel right to you, the strongest move is to skip it -- there is another one tomorrow.