On Tuesday 15 September 2026, Buffalo Bills play Detroit Lions in the NFL. Our model likes 6 bets here. Here is the thinking behind each pick, in plain English.

Buffalo Bills vs Detroit Lions: Detroit Lions (-169)

Odds available at FanDuel at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Detroit Lions. It was priced at -169 when we wrote this, so a $10 bet returns $15.90 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Khalil Shakir (BUF) Under 44.5 Receiving Yards (-114)

Odds available at FanDuel at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Khalil Shakir (BUF) Under 44.5 Receiving Yards. It was priced at -114 when we wrote this, so a $10 bet returns $18.80 if it lands. Our model rates this one a lean pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Buffalo Bills vs Detroit Lions: Buffalo Bills (-312)

Odds available at FanDuel at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Buffalo Bills. It was priced at -312 when we wrote this, so a $10 bet returns $13.20 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Buffalo Bills vs Detroit Lions: Detroit Lions (+195)

Odds available at FanDuel at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Detroit Lions. It was priced at +195 when we wrote this, so a $10 bet returns $29.50 if it lands. Our model rates this one a long shot. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Dalton Kincaid (BUF) Over 2.5 Player receptions alternate (-435)

Odds available at DraftKings at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Dalton Kincaid (BUF) Over 2.5 Player receptions alternate. It was priced at -435 when we wrote this, so a $10 bet returns $12.30 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

Dalton Kincaid (BUF) Over 2.5 Player receptions alternate (-435)

Odds available at FanDuel at time of publishing

Buffalo Bills play Detroit Lions in the NFL on Friday 18 September 2026. The bet we are looking at is Dalton Kincaid (BUF) Over 2.5 Player receptions alternate. It was priced at -435 when we wrote this, so a $10 bet returns $12.30 if it lands. Our model rates this one a strong pick. Prices move, so check the price at your bookmaker before you back it. And if this one does not feel right to you, skipping it is a perfectly good move.

That is how our model reads Buffalo Bills v Detroit Lions. Prices move, so check the price at your bookmaker before you back anything. And if a game does not feel right to you, the strongest move is to skip it -- there is another one tomorrow.

Unlock the rest of this one

You're reading the free preview. One plan unlocks the full article and every pick we back — every league, every day.

Unlock the full article